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https://www.kcl.ac.uk/research/pericles

This research project focuses on developing tools and methodologies for Sickle Cell Disease (SCD) research. We aim to understand how prenatal therapy can be used to treat SCD by developing gene-editing approaches in human and mouse fetal haematopoietic stem cells (HSCs) and delivery methods in a mouse model of SCD. In addition, we aim to generate new knowledge on the ethical considerations and the stakeholders' views on the acceptability of this therapy.

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