Friends I am running the London Marathon on 26th April 2015 and need your support for a hugely worthwhile charity 'Joining Jack' which is fighting to find a cure for muscular dystrophy. 

I am pushing for a sub-four hour finish and hope this will encourage you to dig deep into your pockets. Every Penny helps

Thank you for your support

Paul

Duchenne Muscular Dystrophy is one of the most common fatal genetic disorders to affect children around the world. Approximately one in every 3,500 boys worldwide is afflicted with Duchenne Muscular Dystrophy with 20,000 new cases reported each year in the developed world.

It is a devastating and currently incurable muscle-wasting disease, associated with specific inborn errors in the gene that codes for dystrophin, a protein that plays a key structural role in muscle fibre function. Symptoms usually appear in male children before the age of five. Progressive muscle weakness of the legs and pelvis eventually spreads to the arms, neck, and other areas. By age 10, braces may be required for walking, and most patients are confined to a wheelchair by age 12.

Eventually, this progresses to complete paralysis and increasing difficulty in breathing, requiring ventilation. The condition is terminal, and death usually occurs before the age of 30.

The outpatient cost of care for a non-ambulatory DMD boy is among the highest of any disease. There is currently no cure for DMD, but for the first time ever, there are promising therapies in or moving into clinical development.

Thanks for taking the time to visit my JustGiving page and god willing I will not let you down on the 26th April.

Donating through JustGiving is simple, fast and totally secure. Your details are safe with JustGiving – they’ll never sell them on or send unwanted emails. Once you donate, they’ll send your money directly to the charity. So it’s the most efficient way to donate – saving time and cutting costs for the charity.