Primary sclerosing cholangitis (PSC) is a rare and complex immune-mediated disease of the bile ducts. Symptoms can be severe and unpredictable, sometimes progressing so far that the only lifesaving option is a liver transplant. People with PSC live with an increased risk of developing some cancers, including bile duct cancer and colon cancer. More than three quarters also live with inflammatory bowel disease. Even after a liver transplant, PSC returns in around a third of patients. There is no way to slow or stop the progress of this devastating disease and people living with PSC desperately need a cure. Your donations will help PSC Support to provide much-needed support and information to people affected by PSC. Critically, they'll help PSC Support to fund groundbreaking PSC research, taking us closer and closer to a cure. Every penny counts. Thank you. #LetsBeatPSC