Primary sclerosing cholangitis (PSC) is an immune-mediated disease of the bile ducts with no medical treatment. PSC is referred to as ‘the last black box in hepatology’ because there is so much we don’t yet understand about this complex condition, despite impressive research progress in the last decade. People with PSC urgently need a treatment that works.Donating to PSC Support means you are helping us fund more ground-breaking research projects. The next one could be the breakthrough that people with PSC have been waiting for.#LetsBeatPSC

This disease has touched our family with my husband Jonathan being very sick indeed at times - thankfully he's more stable at the moment - and the wonderful staff in the Hepatic Department at St James Hospital, Leeds, are an enormous help to us.

I'm obviously worried about the run as I haven't run further than about 8km yet! But have a few more weeks of training. In the afternoon we're going to follow it up with an Afternoon Tea with a little entertainment at our church for our friends and family.