Our 2 year-old son, Louie, was diagnosed with High-risk Neuroblastoma and was given a 50% chance of long-term survival at diagnosis. We are desperate for your help.

Up until 19 months of age, Louie was a happy and healthy little boy. He was very active, he loved playing outside, going to the beach and playground, and loved his food - his favourite was cottage pie which he would manage to get everywhere!

However, in June 2023, Louie had become a little less active. He wasn't sleeping well and started to refuse to eat. After a number of visits to the GP, we decided to take him to A&E - something wasn't right - but at that time, we couldn't imagine how severe things could be. Our world was turned upside down when Louie was diagnosed with a rare type of cancer. The cancer is High-risk Neuroblastoma, and at diagnosis, there was a 50% chance of long-term survival.

Since then, Louie has had so much treatment, he has suffered so much, but has still managed to keep his smile throughout. He has had 8 rounds of Chemotherapy, a 10 hour surgery, high-dose chemotherapy and radiotherapy. He has just started immunotherapy.

Initially, the 17 cm long tumour responded very well to treatment and after initial chemotherapy and surgery in October, the tumour was only 0.5 cm. However, the tumour has not responded to treatment since then, and remains that size and is still an active tumour.

If the tumour is not dead upon completing immunotherapy, there remains only a 50% chance of long-term survival. If Louie enters remission before the end of his treatment, there is still a 35% chance of relapse. We have been told there is currently no cure available in the UK in the event of relapse.

We can't sit and hope for the best - we need to act and we need your help. There is a treatment available in the US which has just been approved by the FDA. Early data suggests this treatment, DFMO, is very effective at helping to treat the cancer and in preventing relapse. We are aiming to raise £100,000 in 5 months to make sure we give Louie the best chance of survival and get him to the US for treatment.

We would really appreciate it if you could spread our story and donate if you can comfortably do so.

Thank you.

The total amount will be put towards: 1.Treatment received in the US, 2.Clinical consultations in the US, 3.Any associated testing or scans required in the US, 4.Flights to and from the US and potentially accommodation, 5.Any other cost associated with treatment in the US.

With the treatment recently having been approved by the FDA, pricing of the drug itself is not yet confirmed. Any money received via fundraising which is not spent on the upcoming treatment in the US or associated costs will be kept in a trust, or equivalent. This would then be used to fund future medical treatment Louie may need because of the cancer or side-effects of the treatment he has received.