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The Halton Haven Hospice 2022 event will see hundreds of local people dressed in Santa suits taking part in the 3km fun run from Spike Island in Widnes to the finish by Costa in Runcorn on Sunday 11th December at 10am.
The Silver Jubilee Bridge will be closed to allow the Santas to run across the centre of the bridge.
All the money raised will go directly to the Hospice allowing them to continue to provide a peaceful space, specialist end of life care and support to patients and their families.