Huntington's is fatal disease which damages the brain. Symptoms usually appear between the ages of 30 and 50 and it worsens over time, affecting the person's ability to think, reason, walk and talk, leading to them needing full-time care. Every child of a parent with Huntington's has a 50/50 chance of inheriting the faulty gene, and currently there is no cure. Dr Shouqing Luo and his team at Plymouth University are working with international researchers, clinicians and the pharmaceutical and biotech industries to investigate the potential of manipulating activity at cellular level to find potential effective therapies for this condition. With your support we can move faster and closer to a cure - and bring hope to the estimated 5,700 people in the UK alone with this progressive brain disorder.