Story
Thank you for visiting our page we are raising awareness and funds for the CJD prion research clinic. Below is some information on the Inherited prion diseases which my family carry. In the team there are members Kimberley, Russ, Lee, Emma, Kitty, Nathan, Ewan & Ronnie
Please help donate to this amazing charity as it is so rare and needs more research to help find a way to understand this prion disease more.
Genetics
In inherited prion disease, also known as familial prion disease, a genetic mutation (fault in the gene that codes for the prion protein) causes abnormal prion proteins to be produced in the body, which themselves are predisposed to undergo the change in shape that leads to production of rogue proteins.
The disease runs in families in what is known as an “autosomal dominant” pattern of inheritance. That is, each child who has a parent with inherited prion disease has a 50% chance of having the faulty gene. Those individuals, who do not inherit the mutation and are therefore unaffected, cannot pass the disease on to any of their children. This means that in any affected family it is possible that some; none or all of the offspring will inherit the illness.